Expression of p53 in oligodendrogliomas
نویسندگان
چکیده
منابع مشابه
Expression of p53 in oligodendrogliomas.
The expression of the nuclear protein p53 in oligodendrogliomas was investigated by immunohistochemistry, using a monoclonal anti-p53 antibody (DO-7) on formalin-fixed, paraffin-embedded material in 84 histologically verified cases, and compared with the histopathological grade and survival. p53-immunoreactive cells were found in 75 per cent of the samples acquired at the first biopsy. The p53 ...
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BACKGROUND p53 is a tumor suppressor gene implicated in the genesis of a variety of malignancies including brain tumors. Overexpression of the p53 protein is often used as a surrogate indicator of alterations in the p53 gene. AIMS In this study, data is presented on p53 protein expression in adult cases (>15 years of age) of astrocytic (n=152) and oligodendroglial (n=28) tumors of all grades....
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ژورنال
عنوان ژورنال: The Journal of Pathology
سال: 1993
ISSN: 0022-3417,1096-9896
DOI: 10.1002/path.1711710409